Extraordinary strength of the streptavidin-biotin interaction allows for efficient capturing of even highly dilute targets; however, it makes recovery of proteins from affinity resins challenging. Dde biotin probes eliminate a major limitation of the streptavidin-biotin affinity purification. This reagent contains a biotin moiety linked to an azide moiety through a spacer arm containing a Dde linker. Captured biomolecules can be efficiently released, typically >90%.

ClickChemistryTools(CCT)

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Click Chemistry Tools offers chemical and consulting services mainly in the field of conjugation chemistry. Our experience in the field of conjugation chemistry combined with availability of many click chemistry building blocks at our facility allows us to initiate projects rapidly and to cover a broad range of conjugation chemistry related services.